羊膜移植联合自体角膜缘干细胞移植术治疗伴睑球粘连的复发性翼状胬肉

摘要

目的 评价羊膜移植联合自体角膜缘干细胞移植治疗伴睑球粘连的复发性翼状胬肉的效果.方法 回顾性分析2013年4月至2016年8月收治的12例(12眼)伴睑球粘连的复发性翼状胬肉的临床资料.所有患者均采用羊膜移植联合自体角膜缘干细胞移植手术,术中应用丝裂霉素C.观察胬肉复发情况及有无并发症.结果 术后随访8～ 36个月,1例再次复发,复发率8.33％;其余患者角膜愈合良好,无睑球粘连或眼部组织溶解等并发症.结论 羊膜移植联合自体角膜缘干细胞移植术中应用丝裂霉素C治疗复发性翼状胬肉合并睑球粘连效果良好.%Objective To evaluate the efficacy of amniotic membrane transplantation combined with limbal stem cell autograft transplantation for recurrent pterygium with symblepharon.Methods The data of 12 eyes of 12 cases with recurrent pterygium and symblepharon from Apr.2013 to Aug.2016 were collected and analyzed retrospectively.They underwent amniotic membrane transplantation combined with limbal stem cell autograft transplantation,and the application of mitomycin C during surgery.Results The follow-up period was 8-36 months,pterygium recurred in 1 case after surgery and the recurrent rate was 8.33％.No symblepharon or histolysis complication occurred.Conclusion Amniotic membrane transplantation combined with limbal stem cell autograft transplantation and application of mitomycin C intraoperatively for recurrent pterygium with symblepharon is efficient.