从厚脉络膜相关疾病再认识息肉样脉络膜血管病变

摘要

The fundus appearance of polypoidal choroidal vasculopathy (PCV) often demonstrates orange-red nodular lesions.ICGA reveals terminal dilation of the polyps with or without branching vascular networks.Currently,pachychoroid spectrum disease is a series of conditions included choroidal vasodilatation and increased permeability due to choroidal ischemia,choroidal thickening,retinal pigment epitheliopathy,and secondary pigment epithelial detachment,choroidal neovascularization and polyps included uncomplicated pachychoroid,pachychoroid pigment epitheliopathy,pachychoroid neovascularization,central serous chorioretinopathy,and PCV.These entities have the similar characteristics and prognosis,suggesting that they have the similar pathology.The recognition of PCV based on the pachychoroid spectrum disease can provide new ideas for the prevention and intervention of PCV.%息肉样脉络膜血管病变(PCV)是以眼底橘红色结节样病灶及ICGA病灶处表现为异常分支血管网(BVN)及末端息肉样血管扩张病灶(polyps)为特征的眼底疾病.厚脉络膜相关疾病是以局灶性或弥散性脉络膜增厚,脉络膜血管扩张及通透性增加,存在局灶性Bruch膜及RPE断裂或伴RPE脱离、脉络膜新生血管、polyps为特征的一组疾病,包括无并发症的脉络膜增厚、脉络膜增厚性RPE病变、脉络膜增厚性新生血管病变、中心性浆液性脉络膜视网膜病变、PCV.厚脉络膜相关疾病之间不仅具有相似的形态特征,而且在病变转归方面也存在密切联系,提示其可能具有同源性.从厚脉络膜相关疾病再认识PCV,可为PCV的防治和干预提供新的思路.