小剂量间歇补铁法治疗小儿缺铁性贫血疗效观察

摘要

Objective To study the curative and side effects of small dose of iron supplements on the inter-mittent treatment for children with iron deficiency anemia ( IDA) .Methods 133 children with IDA were divided into two groups, respectively given A group(small doses of intermittent iron supplements) and B group(regular daily dose iron supplement as control group).After two months′treatment, serum ferritin(SF) and hemoglobin(Hb) were de-tected and adverse reactions were observed in the two groups .Results SF and Hb were same after treatment .They were significantly elevated in both groups ( P<0.01 ) .There was no significantly difference between two groups after treatment(P>0.05).The adverse reaction rate of B group was obviously higher than that of A group (P<0.01). Conclusion Small dose of iron supplements of intermittent treatment for the children with IDA is effective and has lower side effects .%目的：研究小剂量间歇补铁法治疗小儿缺铁性贫血（ IDA）的临床疗效及副作用。方法将133例缺铁性贫血患儿半随机分为间歇治疗组（ A组）和常规治疗组（ B组），分别给予小剂量间歇补铁及常规剂量每日补铁治疗，2个月后复查患儿的血清铁蛋白（SF）和血红蛋白（Hb），同时观察并记录患儿不良反应。结果治疗前两组比较SF和Hb基本相同，差异无统计学意义（ P＞0.05），治疗前后比较两组的SF及Hb均显著增加，差异有统计学意义（ P＜0.01）。常规治疗组不良反应发生率明显大于间歇治疗组，差异有统计学意义（ P＜0.01）。结论小剂量间歇补铁法能有效治疗IDA，且药物副作用少、依从性好。