目的：探讨超声挤压征和（或）浸润征在肝脏良恶性微小病变鉴别诊断中的价值。方法对164例共178个经穿刺或手术病理证实直径≤2.0 cm的肝内实质性病变进行二维及彩色多普勒血流显像分析，以肿块挤压征和（或）浸润征作为诊断肝脏微小恶性病变的指标。结果肝脏微小恶性肿瘤挤压征和（或）浸润征检出率（75.24％，79／105）明显高于肝脏良性病变（4.11％，3／73）（P＜0.05）。以有挤压征和（或）浸润征诊断肝脏微小恶性病变的敏感度为75.24％，特异度为95.89％，准确性为83.71％，Kappa值为0.679，ROC曲线下面积为0.846（95％CI＝0.786～0.906）。结论超声挤压征和（或）浸润征在肝脏微小病变的良恶性鉴别诊断中有较大的价值，可为肝脏恶性肿瘤的筛查提供重要的参考。%Objective To investigate the value of compression and /or invasion signs in ultrasonic diagnosis of minimal benign and malignant hepatic tumors.Methods 178 hepatic lesions less than 2.0 cm in 164 cases proved by puncture or operation pathology were examed by the dimensional ultrasonography and color Doppler flow.The com-pression and /or invasion signs were regarded as a criterion of malignant hepatic tumors.Results The detection rate of compression and /or invasion signs in the malignant hepatic minimal lesions(75.24%,79/105) was much higher than that in the benign hepatic minimal lesions(4.11%,3/73)(P<0.05).The sensitivity, specificity and accuracy of the ultrasound in the diagnosis of malignant hepatic minimal tumors were 75.24%, 95.89%and 83.71%respec-tively.The Kappa was 0.679, and the area of ROC was 0.846(95%CI=0.786~0.906) .Conclusion The param-eters of compression and /or invasion signs in ultrasonography can be used for the differential diagnosis of benign and malignant hepatic minimal lesions.
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