Objects To investigate the value of high resolution MRI (HRMRI)in evaluating middle cerebral artery (MCA) symptomatic stenosis. Methods Twenty-five patients with DSA confirmed MCA stenosis of greater than ≥ 30% underwent HRMRI of the MCA. The lumen and wall of the MCA were evaluated on HRMRI. The rates of stenosis were compared between DSA and HRMRI. Results Stenosis was detected in all 16 arteries on HRMRI. Fourteen arteries had wall thickness. Among them, eccentric narrowing lesions were detected in 13 arteries, eccentric enhanced lesions in 12 arteries, both concentric narrowing and enhanced lesions in one artery, no enhanced lesion in one artery. The other two arteries had nearly normal wall thickness with constrictive arterial walls. The difference of stenosis rate between DSA and HRMRI was 0.12 ± 0.05. The stenosis rate of HRMRI was greater than that of DSA (t = 8.702, P< 0.01). Conclusion HRMRI can clearly depict the wall and lumen of MCA and thus is a valuable . tool to evaluate the stenosis of symptomatic MCA.%目的 探讨高分辨率磁共振(HRMMI)斑块成像评估症状性大脑中动脉狭窄程度的价值.方法 对25例DSA确诊的单侧(MCA)症状性狭窄≥50％患者行HRMRI检查,观察HRMRI上MCA狭窄处的管腔和管壁特点,计算狭窄率并与DSA上的狭窄率进行比较.结果 16例MCA在HRMRI上均发现管腔狭窄,14例管壁增厚,其中13例为偏心性增厚；12例偏心性强化,1例无强化；1例为向心性增厚并强化；2例管壁大致正常,外径缩窄.在DSA和HRMRI上测量的狭窄率之差为:10％±5％,HRMRI狭窄率(76％±14％)普遍高于DSA狭窄率(64％±11％)(t=8.702,P＜0.05).结论 HRMRI能清晰的显示症状性MCA狭窄的管腔和管壁特点,对于MCA狭窄的诊断有一定参考价值.
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