电流感觉阈值在糖尿病周围神经病变诊断中的评价

摘要

目的 利用电流感觉阈值测定与神经传导速度的比较,探讨电流感觉阈值对糖尿病周围神经病变的诊断价值.方法 60例确诊为2型糖尿病患者,分别进行感觉神经传导速度(sense nerve conduction velocity,SNCV)和电流感觉阈值(current perception threshold,CPT)测定,比较SNCV和CPT的异常率.结果 CPT检查异常率68.33％,SNCV检查异常率36.67％;有症状组中CPT检查异常率88.46％,SNCV检查异常率53.85％;无症状组中CPT检查异常率47.06％,SNCV检查异常率17.65％;病程≤5年组中CPT检查异常率55.17％,SNCV检查异常率24.14％;病程>5年组中CPT检查异常率77.42％,SNCV检查异常率48.39％.两种检查方式对比差异具有统计学意义(P<0.05).结论 CPT检查和NCV检查对糖尿病周围神经病变的诊断具有一致性,对于早期无症状患者,CPT检查对亚临床患者更有诊断优势.%Objective To evaluate the diagnostic value of current perception threshold (CPT) for diabetic peripheral neuropathy by comparing with nerve conduction velocity (NCV). Methods Sixty patients with type 2 diabetes were enrolled. The CPT and SNCV were examined respectively. Results The abnormal rates of the CPT and SNCV were 68.33％and 36.67％in all patients, respectively. The abnormal rates of the CPT and SNCV were 88.46％and 53.85％in symptomatic group. The abnormal rates of the CPT and SNCV were 47.06％ 17.65％ in asymptomatic group. In patients with disease less than five years, the abnormal rates of the CPT and SNCV were 55.17％ and 24.14％. In patients with disease greater than five years, the abnormal rates of the CPT and SNCV were 77.42％ and 48.39％. The abnormal rate was statistically significant difference (P<0.05) between two examination. Conclusion CPT and NCV were consistency in the diagnosis of diabetic peripheral neuropathy. For early asymptomatic patients, CPT have more advantages to inspect the sub-clinical patients.