目的 应用超声心动图技术优化调节心脏再同步化治疗(CRT)的疗效.方法 接受CRT的慢性心力衰竭患者30例,在超声心动图引导下进行优化AV间期和VV间期.结果 30例患者CRT优化后心功能得到改善,左室充盈时间较优化前增加,二尖瓣返流减少；左室内各室壁收缩期达峰时间标准差减少,左室流出道速度时间积分上升,左室收缩末容积减少.结论 超声引导下AV间期和VV间期优化能够提高CRT临床疗效.%Objective To study the value of echocardiography-guided pacemaker parameters optimization in enhancing the efficacy of cardiac resynchronization therapy (CRT). Methods Thirty patients with chronic heart failure received biventricular resynchronous pacing therapy. An optimization procedure was performed with different AV and VV delays. Results The indices of heart function were significantly improved after CRT optimization. Left ventricular filling time (LVFT) was increased, mitral reflux (MR) was decreased, standard deviation of time to regional peak systolic velocity (Ts-12SD) was decreased, left ventricular outflow tract velocity time integral (VTILVOT) was increased, and the end of the left ventricular systolic volume (LVESV) was decreased. Conclusions Echocardiography-guided optimization of AV and VV delay can enhance the efficacy of CRT.
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