首页> 中文期刊>中华老年多器官疾病杂志 >老年血行播散型肺结核临床特征及转归分析

老年血行播散型肺结核临床特征及转归分析

     

摘要

目的:探讨老年血行播散型肺结核( DPT)的临床特点及转归。方法入选2006年1月至2014年4月期间在北京老年医院感染疾病科进行治疗的DPT患者96例。根据年龄将所有患者分为两组:老年组( n=42)和非老年组( n=54)。回顾性分析两组患者的临床特点和转归。结果老年组患者合并症发生率显著高于非老年组(66.7% vs 24.1%;P=0.000)。与非老年组相比,老年组患者的结核菌素试验( PPD)阳性率、血红蛋白含量和白蛋白含量均显著降低,而白细胞计数显著增加(P<0.05)。老年组患者的误诊率显著高于非老年组(45.2%vs 24.1%;P=0.029)。与非老年组相比,老年组患者的治愈率显著降低(52.4%vs 77.8%;P=0.009),而死亡率显著增高(11.9% vs 1.9%;P=0.044)。结论老年DPT患者治愈率低,误诊率和死亡率高,临床应予以充分重视。%Objective To investigate the clinical characteristics and outcome of the aged patients with disseminated pulmonary tuberculosis ( DPT) .Methods A total of 96 patients with identified DPT admitted in our department from January 2006 to April 2014 were subjected in this study .According to their age , they were divided into the aged group ( n =42 ) and the non-aged group (n=54).The clinical features and outcomes of 2 groups of patients were retrospectively analyzed .Results The aged group had a significantly higher incidence of complications than the non-aged group (66.7%vs 24.1%, P=0.000).The positive rate of tuberculin purified protein derivative ( PPD) test, and the levels of hemoglobin and albumin were obviously lower in the former than in the latter group (P<0.05).Compared with the non-aged group, the patients of the aged group had significantly higher misdiagnosis rate (45.2%vs 24.1%, P=0.029), lower recovery rate (52.4% vs 77.8%, P=0.009) and higher mortality (11.9% vs 1.9%, P=0.044).Conclusion The aged DPT patients have lower recovery rate , higher mortality and misdiagnosis rate .Special attention should be paid to them in clinical practice .

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