Objective To evaluate the efficacy of ureteroscopic holmium laser lithotripsy for the treatment of ureteral stones . Methods One hundred and four cases of ureteral stones , including 22 cases of proximal stones and 84 cases of middle or distal ureteral stones, were treated with holmium laser lithotripsy under ureteroscopy with a top energy of 1.0-1.5 J and a pulse frequency of 10-15 Hz.The lithotripsy was employed from the outside to the central , and stones were fragmented into particles less than 3 mm in diameter. Results Lithotripsy was successful in 97 cases.The successful rate was 93.3% (97/104) for all the cases, with 77.3%(17/22)for proximal cases, and 97.6%(80/82)for middle or distal cases.Three cases were converted to extracorporeal shock wave lithotripsy because stones were driven back to renal pelvis .Four cases were converted to open surgery because of severe distortion of the ureter.The mean operation time was 44.5 min (12 -105 min).The postoperative hospitalization ranged 3 -7 d (mean, 4.5 d).Four cases were complicated with mild ureteral perforation , all of which were cured 1 month after insertion of double J ureteral catheter.No severe complications such as ureteral laceration were observed .Urinary tract infection and fever were observed in 12 cases.Follow-up of 97 cases for 1 -12 months ( mean, 4 months ) showed all were stone free within one month after surgery . Conclusion Ureteroscopic holmium laser lithotripsy is a safe and efficacious treatment for ureteral stones .%目的：探讨输尿管镜钬激光碎石术治疗输尿管结石的疗效。方法2010年6月～2013年12月对104例输尿管结石（输尿管上段结石22例，中、下段结石82例）行输尿管镜下钬激光碎石，钬激光能量1．0～1．5 J，脉冲频率10～15 Hz，采用蚕食法，从结石周边向中央行碎石治疗，将结石粉碎成直径＜3 mm颗粒。结果97例一次碎石成功，成功率93．3％（97／104），其中上段结石碎石成功率77．3％（17／22），中、下段结石为97．6％（80／82）。3例结石冲回肾盂，改体外冲击波碎石治疗；4例因输尿管严重扭曲置镜失败，改开放手术。手术时间12～105 min，（44．5±21．7）min。术后住院时间3～7 d，（4．5±1．5）d。4例输尿管小穿孔，置双J管1个月后痊愈，无一例出现输尿管撕裂等较为严重的并发症；12例发生泌尿系感染与发热。97例随访1～12个月，平均4个月，术后1个月内结石全部排净。结论输尿管镜钬激光碎石术治疗输尿管结石安全，疗效可靠。
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