超声支气管镜引导针吸活检在纵隔及肺门淋巴结肿大中的临床应用

摘要

目的探讨超声支气管镜引导针吸活检术（ endobronchial ultrasoundguided transbronchial needle aspiration ，EBUS-TBNA）在纵隔及肺门淋巴结肿大诊断中的应用价值。方法回顾性分析我院2013年10月～2016年10月EBUS-TBNA检查105例资料，其中纵隔淋巴结肿大102例，肺门淋巴结肿大3例。结果 EBUS-TBNA病理确诊恶性91例，良性14例。良性中的6例非特异性淋巴结炎经手术复检5例为恶性，1例确诊良性。恶性肿瘤诊断准确率95．2％（100／105），敏感度94．8％（91／96），特异性100％（9／9），阳性预测值100％（91／91），阴性预测值64．3％（9／14）。结论 EBUS-TBNA安全、有效，敏感度和特异度高。%Objective To investigate the value of endobronchial ultrasound guided transbronchial needle aspiration ( EBUS-TBNA) in the diagnosis of mediasyinal and hilar lymph node enlargement . Methods A retrospectively study was analyzed in 105 patients with mediastinum and hilum lymph node enlargement (102 patients with mediastinum lymph node enlargement and 3 patients with hilum lymph node enlargement ) who received EBUS-TBNA from October 2013 to October 2016 in our hospital . Results Of the 105 patients, EBUS-TBNA gave a preliminary pathology of 91 malignant cases and 14 benign cases.Among the 14 benign cases, there were 6 patients with nonspecific lymphadenitis , 5 of which were confirmed as malignant and 1 of which was diagnosed benign with re-inspection by surgery.The malignant tumor diagnosis accuracy rate was 95.2%(100/105), the sensitivity of malignant tumor was 94.8%(91/96), and the specificity was 100% (9/9).The positive predictive value was 100% (91/91), and the negative predictive value was 64.3% (9/14). Conclusion EBUS-TBNA is a safe and effective examination method in the diagnosis of mediasyinal and hilar lymph node enlargement .