The tissue oxygen consumption of the heart, kidney, brain, liver, intestine of the rats, which are divided into normal contrast group, hemorrhagic shock group, Anisodamine(654 2) group, N Butyl Scopdammonium group and Anisodus tanguticus group(all n =10), were measured by using the Oximeter for biological materials. The results showed that the oxygen consumption of intestinal musoca was highest, then the kidney, brain, liver, heart, and the oxygen consumption of intestinal serosa was lowest among all. The oxygen consumption of the brain, kidney, intestinal muscle in hemorrhagic shock group was significantly higher than that of the normal contrast group, probably because the kidney, brain and intestinal muscle needed a great deal of oxygen in order to keep themselves functional in the ischemic and hypoxic states. 654 2, N Butyl Scopolammonium Bromide, and Anisodine were injected(5 mg/kg. iv.) 10 minutes before hemorrhage. The outcomes indicated that 654 2 could significantly prevent the oxygen consumption of all the above organs from increasing after hemorrhagic shock, probably because 654 2 could keep lysosome stable and improve the tolerance of Mitochondria to hypoxia. N Butyl Scopolammonium Bromide and Anisodine could keep the oxygen consumption of intestinal musoca and liver from increasing after the hemorrhagic shock, but they had no significant effect on the oxygen consumption of the heart, brain and kidney.
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