食管癌病理特点及治疗预后的影响因素研究

摘要

目的探究食管癌病理特点及治疗预后的影响因素。方法将本院2008年1月至2012年12月收治的247例食管癌的患者作为研究对象，研究食管癌病理特点。随诊3年研究分析影响治疗预后的相关因素。结果食管癌病理特点以老年男性、肿块长度小于5cm、鳞癌、组织学中、高分化、神经侵犯多见（P＜0.05）。而肿块位置、有无淋巴结转移方面并无明显特异性，差异不具有显著性（P＞0.05）。3年的随访结果所示，247例食管癌患者3年生存率为62.75%。患者的年龄、肿块长度、组织学分型、淋巴结转移、神经侵犯、TNM分期均是影响食管癌治疗预后的主要影响因素（P＜0.05）。结论食管癌病理特点直接影响治疗预后情况，临床上需更加关注食管癌病例特点，正确评估疾病发展趋势。%Objective To explore pathological characteristics of esophageal cancer and its influencing factors on prognosis.Method247 patients with esophageal cancer who were treated in our hospital from January 2008 to December 2012 were studied to investigate the pathologic characteristics of esophageal cancer.Three years follow-up for observation of the prognosis of influencing factors.Result Pathological characteristics of esophageal cancer in elderly men,tumor length less than 5cm,squamous cell carcinoma, high differentiation, nerve invasion more common (P<0.05). But there was no significant difference in lymph node metastasis and lymph node metastasis (P>0.05). 3-year follow-up results showed that 247 cases of esophageal cancer patients 3-year survival rate was 62.75%. The age, tumor size, histological type, lymph node metastasis, nerve invasion and TNM staging were the main factors influencing the prognosis of esophageal cancer (P<0.05).ConclusionThe pathological characteristics of esophageal cancer directly affect the prognosis of treatment.Clinical need to be more concerned about the characteristics of cancer and the correct assessment of disease trends.