血清降钙素原和C-反应蛋白检测在下呼吸道患者治疗中的临床意义

摘要

目的：探讨血清降钙素原(PCT)和C-反应蛋白(CRP)检测在下呼吸道患者治疗中的临床意义。方法：收集邢台市第一医院2012年1月～2013年12月就诊的下呼吸道感染患者100例作为下呼吸道感染组（A组），选择同期健康体检人群50例作为健康对照组（B组），血清CRP检查采用免疫比浊法,PCT用固相夹心酶联免疫吸附法进行测定。结果：A组血清CRP、PCT均显著高于B组（P<0.01)；A1组血清CRP、PCT均显著高于A2组（P<0.01)；PCT检测指标明显高于PCT检测指标（P<0.05)。结论：PCT及CRP都能够用于细菌感染的早期诊断， PCT检测指标均高于CRP，细菌培养及药敏实验是细菌感染诊治的重要依据。%Objective: To explore the signiifcance of serum procalcitonin(PCT) and C- reactive protein(CRP) detection and clinical signiifcance in the treatment of patients with lower respiratory tract. Methods: Collected in 2012 January to 2013 December in Xingtai First Hospital treatment of patients with lower respiratory tract infection in 100 cases as the lower respiratory tract infection group(group A), select the same period 50 cases of healthy people as healthy control group(group B), serum CRP was detected by immune turbidimetry, PCT by solid phase sandwich enzyme linked immunosorbent assay for determination Results: The serum CRP, PCT of A group were signiifcantly higher than in group B(P<0.01);group A1, serum CRP, PCT were signiifcantly higher than that in A2 group(P<0.01);the PCT index was signiifcantly higher than that of PCT index (P<0.05). Conclusions: PCT and CRP can be used for early diagnosis of bacterial infection, PCT indexes were higher than that of CRP, bacterial culture and drug sensitive experiment is an important basis for the diagnosis and treatment of bacterial infection.