基于EDose软件电子射野影像系统的调强剂量验证

摘要

Objective To investigate the feasibility of electronic portal imaging device (EPID) for the three-dimensional dosimetric verification of intensity-modulated radiotherapy (IMRT) plan. Methods The IMRT plans of 10 patients were verified with two systems, namely EDose software-based EPID of Varian Trilogy Linacs and Mapcheck system from Sun Nuclear Corporation with the matching phantom. The gamma passing rates of absolute dose and relative dose in two systems was recorded and analyzed. Results When the gamma standard (3％/3 mm) was applied, the gamma passing rates of relative doses in EPID and Mapcheck system were (98.51％±1.10％) and (98.73％±0.69％), respectively, and those of absolute doses were (96.50％±3.33％) and (97.64％±1.51％), respectively, without any statistical differences (P>0.05). For the other standards, the differences in gamma passing rates between EPID and Mapcheck system were statistically significant. Conclusion EPID is more convenient and efficient than Mapcheck system and can be used as a tool for three-dimensional dosimetric verification of IMRT plan.%目的:探讨电子射野影像系统(EPID)用于调强放射治疗三维剂量验证的可行性.方法:分别使用Varian公司的Trilogy加速器自带的EPID及EDose软件和美国Sun Nuclear公司的Mapcheck剂量验证系统及配套模体对10例调强放射治疗的患者进行剂量验证,记录并比较分析两种系统的绝对剂量和相对剂量γ通过率的相关性.结果:采用γ(3％/3 mm)标准时,相对剂量EPID和Mapcheck验证的γ通过率分别为(98.51％±1.10％)、(98.73％±0.69％);绝对剂量EPID和Mapcheck验证的γ通过率分别为(96.50％±3.33％)、(97.64％±1.51％),两者均无统计学意义(P>0.05).其它标准的γ通过率有统计学意义.结论:EPID可以作为调强三维剂量验证的工具,比Mapcheck更方便快捷.