胰腺癌伽马刀和螺旋断层放疗治疗计划剂量学比较

摘要

Fourteen patients with pancreatic carcinoma were selected. Two treatment plans were designed for each patient, including g knife and Tomtherapy. The dose characteristics were evaluated by DVH and were compared. The results showed that the g knife plan had the higher maximal and mean target dose than Tomotherapy. Body g knife can increase the target dose significantly, and decrease the OAR dose. Tomotherapy had excel ent dose-target conformality, and it can control doses of duodenum and stomach easily, but it had larger low dose region.%　　选取14例胰腺癌病例，均用Tomotherapy和伽马刀两种治疗计划。通过DVH计算靶区剂量和周围要害器官剂量。得出伽马刀计划靶区剂量比Tomotherapy高，伽马刀可显著提高胰腺癌靶区剂量，减少周围正常组织剂量。Tomotherapy有很高的适形度，优于伽马刀，能很好控制十二指肠和胃的最高剂量，但低剂量区范围较大。