肿瘤血管生成异质性及肿瘤血管生成超声分子靶向成像研究进展

摘要

肿瘤血管具有结构紊乱和功能不全的特征,肿瘤间质中新生微血管内皮分子遗传学和微血管构筑的异质性是近年来研究的热点,也是肿瘤血管生成超声分子靶向成像的研究基础.本文对肿瘤血管生成异质性及肿瘤血管生成超声分子靶向成像研究进展进行综述.%Tumor blood vessels are characterized with insufficiency and distortion. Endothelial molecules of neovascularization and the heterogeneity of microvasculature in tumor interstitial are the basis for molecular-targeted ultrasonic evaluation of tumor angiogenesis, and has become focus in recent years. Research progresses of molecular-targeted ultrasonic imaging in angiogenesis and heterogeneity of tumors were reviewed in this article.