SPGR-T2*W T2*值定量分析鉴别脑出血和钙化

摘要

目的 评估SPGR-T2*W序列T2*值定量分析发现和鉴别脑出血与钙化的价值.方法 对经T2* WI的三维梯度回波序列动脉成像(ESWAN)确诊的18例脑出血患者(38个病灶)和7例颅内钙化患者(11个病灶)进行MR SPGR-T2*W (15 ms/30 ms)检查,测量不同病灶的T2*值并进行统计学分析.结果 出血核心区与钙化的T2*值有统计学差异(P＜0.001),但出血外周区与钙化的T2*值无统计学差异(P＞0.05).结论 结合其他序列的信号强度变化,SPGR-T2*W序列T2*值定量分析可发现和鉴别脑出血与钙化,有利于实现脑血管病的一站式MR诊断.%Objective To investigate the value of SPGR-T2' weighted MR imaging sequence and quantitative analysis of T2" values in the diagnosis and differential diagnosis between cerebral hemorrhage and calcification. Methods SPGR-T2' weighted imaging with TE of 15 ms and 30 ms were performed in 18 patients of cerebral hemorrhage (38 lesions) and 7 patients of calcification (11 lesions). All patients had been diagnosed by enhanced gradient echo T2 star weighted angiography (ESWAN). T2' values of all lesions at different TE values were recorded, and then statistical analysis was made. Results T2' values with different TE were statistically different between core areas of cerebral hemorrhage and calcification lesions (P<0. 001). No statistical difference was found in T2* values between peripheral areas of cerebral hemorrhage and calcification lesions (P>0. 05). Conclusion Combining with signal changes at other sequences, the quantitative analysis of SPGR-T2" weighted's T2 * value with different TE is able to diagnose and differentiate cerebral hemorrhage and calcification, therefore, it is helpful for one-stop MR diagnosis of cerebrovascular diseases.