Objective To assess the short-effect of cardiac resynchronization therapy (CRT) on right ventricular (RV) systolic function and synchrony with TDI. Methods Fifty-one heart failure patients underwent conventional ultrasonogra-phy and TDI examination before and 1 month after CRT. RV dimension (RVD), lateral wall tissue velocity (RVv) and RV dyssynchrony (RV-T) were detected. Meantime, left ventricular end-systolic volume (LVESV), left ventricular ejection fraction (LVEF), and dyssynchrony (LV-TSD) were assessed. Patients with reduction ≥15% in LVESV 1 month after CRT were classified as responders. Parameters were compared between preoperation and postoperation. Results Thirty-eight patients (38/51, 74.51%) were classified as responders, and 13 were classified as nonresponders (13/51, 25. 49%). RVD did not change, but RVv and RV-T increased significantly in both responders and non-responders after CRT. And the improvement of RVv correlated with RVv and RV-T before CRT (r=0. 69, -0. 73, P<0. 05), while did not correlate with LV-TSD. Conclusion CRT can promptly increase the RV systolic function and synchrony in short time.%目的 采用TDI评价心脏再同步化治疗(CRT)对右心室(RV)收缩功能和同步性的短期影响.方法 对51例因慢性心力衰竭(CHF)而接受CRT治疗的患者,于术前和术后1个月行常规超声心动图和TDI检查,检测右心室内径(RVD)、游离壁收缩期峰值速度(RVv)和同步性(RV-T),同时检测左心室收缩末期容积(LVESV)、射血分数(LVEF)和同步性(LV-TsD).以术后1个月LVESV减小率△LVESV≥15％为CRT治疗有效,比较术后与术前各参数的变化.结果 CRT术后38例患者(38/51,74.51％)为有效组,13例(13/51,25.49％)为无效组.两组术后RVD无变化,右心室收缩功能(RVv)和同步性(RV-T)均显著改善,RVv改善率与术前RVv和RV-T密切相关(r=0.69、-0.73,P＜0.05),而与LV-TsD无相关.结论 短期CRT即可显著改善右心室收缩功能和同步性.
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