Objective To compare pulmonary regurgitation (PR) measured with 3. OT phase contrast MRI (PC-MRI) and echocardiography, in order to evaluate the relationship between PR and right ventricle (RV) volume as well as RV systolic function. Methods Cardiac MRI and echocardiography were performed within a month after surgical correction of tetralogy of Fallot (TOF) in 42 patients. The pulmonary regurgitation fraction (PRF) was calculated with PC-MRI. Correlation a-nalysis for mild, moderate and severe PRF was performed between PC-MRI and echocardiography. Right ventricle end di-astolic volume index (RV-EDVI), right ventricle end systolic volume index (RV-ESVI) and right ventricle ejection fractions (RVEF) were compared among different degrees of PRF. Results Degrees of PR measured with PC-MRI had positive correlation with the results of echocardiography (rs = 0. 606, P<0. 001). RV-EDVI of mild, moderate and severe PRF was 89. 45, 108. 05 and 133. 50 ml/m2, while RV-EDSI was 50. 40, 64. 85 and 81. 30 ml/m2 , respectively. RV-EDVI and RV-ESVI had statistical difference among mild, moderate and severe PRF (χ2= 12. 530, 13. 173, both P<0. 01), but no difference of RVEF was found (χ2=0. 032, P>0. 05). Conclusion PRF measured with 3. 0T PC-MRI has good correlation with results of echocardiography. RV-EDVI and RV-ESVI have close relationship with PR. RV-EDVI and RV-ESVI increase with PR deteriorates, but RV-EF keeps stable.%目的 通过3.0T相位对比磁共振(PC-MRI)定量测量法洛四联症(TOF)术后远期患者的肺动脉反流程度,并与超声心动图结果进行分析,评价肺动脉反流与右心室容量及收缩功能的关系.方法 对42例TOF根治术后患者于1个月内先后接受超声心动图及心脏MR检查.以PC-MRI测量肺动脉反流分数(PRF),分为轻度、中度、重度；对PC-MRI所见与超声心动图测量的PRF程度进行相关分析.比较不同PRF程度间右心室舒张末容积指数(RV-EDVI)、右心室收缩末容积指数(RV-ESVI)、右心室射血分数(RVEF)的差异.结果 PC-MRI与超声心动图显示的肺动脉反流严重程度呈正相关(rs=0.606,P＜0.001).轻度、中度及重度PRF组RV-EDVI中位数分别为89.45、108.05及133.50 ml/m2(x2=12.530,P=0.002),RV-ESVI中位数分别为50.40、64.85及81.30 ml/m2(x2=13.173,P＜0.01),但三组间RVEF差异均无统计学意义(x2=0.032,P＞0.05).结论 3.0T PC-MRI测量肺动脉反流严重程度与超声心动图有良好相关性.RV-EDVI及RV-ESVI与肺动脉反流程度密切相关；随反流严重程度加重,RV-EDVI及RV-ESVI增大,而RVEF保持稳定.
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