应用1H NMR技术对一些以[2+4]环加成方式合成出的苯并二氮杂卓的立体化学进行了研究.利用偶合常数和gNOESY的结果,证明了二氮杂卓七员环的扭船式溶液构象,并与其类似的苯并硫氮杂卓作了比较和讨论.%A series of 1,3-oxazino［3,2-d］［1,5］ benzodiazepine-1-one derivatives' stereochemistry was studied by 1H NMR. During the 1H NMR experiments, we found out their unique stereochemistry of seven-membered rings. All the discernible hydrogen's chemical shifts were assigned. Their distorted boat conformations were discovered by the related coupling constants and gNOESY results, which were compared with x-ray diffraction result and the conformation of analogous benzothioazepines.
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