自身免疫性脑炎(AE)是一类新发现的中枢神经系统自身免疫性疾病,其病因复杂,症状特异性不高,在诊断上存在较多困难.AE的临床诊断应结合其临床特点、实验室的相关检查、脑电图和头部影像学等检查综合判断.尤其是AE相关自身抗体的检测对诊断有重要价值,部分自身抗体对体内潜在肿瘤的发生也有很强的提示作用,并且可为治疗和预后提供参考.%Autoimmune encephalitis(AE)is a kind of newly discovered autoimmune disease of the central nervous system.The cause of autoimmune encephalitis is complex and symptoms are lacking in specificity.There are many difficulties in diagnosis of AE.The clinical diagnosis of AE should be combined with its clinical characteristics, the detection of AE-related autoantibodies and laboratory-related tests, electroencephalogram, head imaging, et al.AE-related autoantibody detection is more helpful in the diagnosis,some of the autoantibodies also have a strong hint of potential tumor in the body,and can help to determine the treatment and prognosis.
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