三维超声引导下经房间隔穿刺消融左心室前乳头肌室性早搏

摘要

Objective To investigate ablation characteristics of PVC/VT originating from left ventricle anterior papillary muscles.Methods This study included 10 patients of PVC/VT originating from left ventricle anterior papillary muscles from January 2015 to June 2016 in Beijing Anzhen Hospital.Electrophysiological mapping and radiofrequency ablation were completed using three-dimensional anatomical mapping system combined with three-dimensional intracardiac ultrasound technology.ECG and abaltion target diagram characteristics as well as the special anatomy were explored.Results All the 10 patients were successfully ablated and followed up for 12 months.One patient had recurrence within 12 months and no complications were recorded.The target sites localized at the tip (n =1),middle portion(n =4)or the base (n =5) of the LV-APM.Among 7 patients,the target sites were located at the anterior septal papillary muscle and in 3 patients were located in the free papillary muscle.9 patients were successfully ablated via anterograde trans-septal catheterization after the failure of retrograde approach.Premature QRS wave time were 152.80 ± 11.72 ms and 6 patients presented sharp potential at the targets during PVC/VT.Conclusions PVC/VT originating from left ventricle anterior papillary muscles have similar ECG and diagram characteristics that is different from which originating from left anterior fascicle.It is recommended to get the target via transseptalpuncure approach.Ablation target could be clearly positioned by three-dimensional intracardiac ultrasound technology.%目的 探讨左心室前乳头肌起源的室性早搏(premature ventricular contraction,PVC)消融特征.方法 纳入2015年1月至2016年6月北京安贞医院收治的10例左心室前乳头肌起源的PVC/室性心动过速(ventricular tachycardia,VT),采用三维电解剖标测系统联合三维心腔内超声技术,术中经三维超声证实有效靶点位于左心室前乳头肌,完成电生理标测和消融.分析该部位起源的PVC/VT的心电图特征、腔内靶点图特点、解剖结构等消融特点.结果 10例患者均成功消融,随访12个月1例复发,均未出现相关并发症.靶点分别位于乳头肌近腱索处1例、中段4例及基底部5例;7例位于间隔前乳头肌,3例位于游离壁乳头肌;1例穿刺右侧股动脉,9例经右侧股静脉入径,穿刺房间隔顺行法消融成功.早搏QRS波时限(152.80±11.72)ms,其中6例患者在PVC/VT时靶点处可记录到提前的高频电位.结论 左心室前乳头肌起源PVC/VT心电图有别于左前分支起源PVC/VT的特征,经房间隔穿刺途径容易到达靶点位置,应用三维超声可准确定位左心室前乳头肌起源室性心律失常消融靶点.