长期有氧运动对改善亚健康人群心肺功能、红细胞免疫功能及T淋巴细胞变化的影响

摘要

目的：探讨长期有氧运动对改善亚健康人群心肺功能、红细胞免疫功能及 T淋巴细胞变化的影响。方法选取2012年8月—2014年8月的112例亚健康人群进行干预分析,随机分为试验组和对照组,各56例。对照组进行常见运动,试验组采用有氧运动。对进行有氧运动前后的心血管功能、肺功能进行测定,分析两组病人运动前后亚健康人群心肺功能的改善情况。结果试验组的安静心率(68.6±1.2)次/min、收缩压(122.6±11.5)mmHg、舒张压(65.8±2.5)mmHg、脉搏压(43.6±1.2)mmHg和心功指数(116.9±10.3)L· kPa/(min· m2),均明显优于对照组,具有统计学意义(P<0.05)。试验组的肺活量(VC)为(4.9±0.9)L、用力肺活量(FVC)为(3.2±0.5)L、每分钟最大通气量(MVV)为(116.8±12.5)L,明显优于对照组,具有统计学意义(P<0.05)。试验组受试者运动后血液中 RBC C3bRR(6.95±0.79)和 RBC ICR(17.53±1.44)比例与对照组对比,具有统计学意义(t=6.291,P<0.05),试验组受试者在 T3时段内 T淋巴细胞亚群 CD3+、CD4+、CD8+比例及 CD4+/CD8+比值均持续下降,且于 T4时段内逐渐恢复到运动前的安静状态,运动前后 T淋巴细胞及其亚群无明显变化,组间对比无统计学意义(t=0.281,P>0.05)。结论对亚健康人群进行有氧运动可以更好地改善心血管功能、肺功能。%Objective To investigate the effects of long term aerobic exercise on improving cardiac and pulmonary function,red blood cel immune function and T lymphocyte changes in sub healthy people. Methods One hundred and twelve healthy people from Au-gust 2012 to August 2014 were randomly divided into experimental group and control group,56 cases in each group. The control group was used for common exercise.Cardiovascular function and pulmonary function were measured before and after aerobic exer-cise,and the improvement of cardiopulmonary function in two groups of patients before and after exercise were analyzed. Results The quiet heart rate,systolic blood pressure,diastolic blood pressure,pulse pressure and cardiac function index of the experimental group were significantly better than those of the control group (P<0.05). VC (4.9± 0.9)L,FVC (3.2± 0.5)L,MVV (116.8± 12.5)L in experimental group was significantly better than that in control group (P<0.05). There was significant difference in blood rbc c3brr and RBC ICR proportion between experimental group and control group (P<0.05).The experimental group subjects in T3 period T lymphocyte subsets CD3+,CD4+,CD8+ratio and ratio of CD4+ /CD8+ decreased continual y and in T4 period gradual y returned to the pre exercise quiet state,there was no obvious change T lymphocyte and subsets befor and after the exercise,be-tween two groups(P>0. 05). Conclusion Aerobic exercise can improve the cardiovascular function,and lung function in sub healthy people.