急性呼吸窘迫综合征的诊断及呼吸支持治疗进展

摘要

Acute respiratory distress syndrome (ARDS) is a clinical syndrome characterized by progressive hypoxemia and respiratory distress, which occurs in the course of critical illness, and diffuse interstitial and alveolar edema caused by injury of alveolar capillary endothelial cells and alveolar epithelial cells, the overall morbidity and mortality of ARDS are still high. In recent years, with a better understanding of ARDS, more and more researches on this subject have been made, establishing a new concept for the diagnosis and treatment of ARDS. Early respiratory function support and correction of hypoxia are the main measures for treatment of ARDS, and mechanical ventilation is still a primary method for respiratory support of ARDS patients. In this review, we present a summary of the modern advance in diagnosis and respiratory support for treatment of ARDS.%急性呼吸窘迫综合征(ARDS)是发生于危重疾病过程中,由于肺泡毛细血管内皮细胞和肺泡上皮细胞损伤引起的弥漫性肺间质及肺泡水肿,表现为进行性低氧血症、呼吸窘迫为特征的临床综合征,其总体发病率和病死率目前仍居高不下.随着人们对ARDS认识的不断深入,近年来,越来越多的研究奠定了ARDS新的诊疗理念,早期呼吸功能支持、纠正低氧血症是ARDS治疗的首要任务,机械通气仍是ARDS患者的主要的呼吸支持手段,现就ARDS的诊断及呼吸支持治疗进展综述.