Experimental Study on Treatment of SIV Infection by Zhongyan No. II In Monkeys

摘要

Objective: To investigate the curative effect of Zhongyan No. II (ZY II ) in treating SIVmac251 infection in macaques monkeys and evaluate the anti-viral effect of the drug as well as its protection on organism. Methods: Using SIVmac251 infected monkey model to detect the plasma SIVP 27 antigen level by viral isolation and ELISA; determine the T-lymphocyte subsets CD4 and CD8 by indirect immunofluorescence and flow cytometry, and investigate the serum content of neopterin and B2-mi-croglobulin B2-MG)by ELISA. The pathological examination was conducted as well. Results: ZY