硫化铜空心球的合成和生长机理及其在抗肿瘤中的应用

摘要

以Cu(NO3)2·3H2O,H2C2O4和Na2S·9H2O为原料,利用简易水热方法合成了笼状硫化铜空心球.所得产物用X射线衍射(XRD)、场发射扫描电子显微镜(FE-SEM)、透射电子显微镜(TEM)和高分辨透射电子显微镜(HRTEM)进行了表征,并研究了其可能的形成机理.所得CuS空心球具有较高的光热转换性能,在近红外光辐照下,对肿瘤细胞具有明显的光热毒性.%Cage-like hollow morphologies of copper sulfide nanostructures have been selectively synthesized using cupric nitrate trihydrate (Cu(NO3)2·3H2O),oxalic acid (H2C2O4) and sodium sulphide nonahydrate (Na2S·9H2O) as starting materials in water solution by a self sacrificing templates hydrothermal method.X-ray diffraction (XRD),field scanning electron microscopy (FESEM),transmission electron microscopy (TEM) and high-resolution transmission electron microscopy (HRTEM) were used to characterize the products.The possible formation mechanism of CuS hollow spheres was proposed.The photo-thermal conversion experiments were also done.The results showed that hollow CuS exhibited high photo-thermal efficiency and high anticancer activity under NIR irradiation.