新型Co(salen)化合物的合成,表征及其硫醚不对称氧化反应

摘要

New Co(salen) complexes (2a～2c and 3a～3c) have been synthesized and characterized. Chiral Co Ⅱ (salen) complexes 2a～2c showed moderate reactivity with poor enantioselectivity (8%～21% ee) in asymmetric oxidation of PhMeS, but no reaction was observed for ehiral CoⅢ(salen) complexes 3a～3c. Lower asymmetric induction has been discussed by considering the conformation effect of the ligand.%合成并表征了新的Co(salen)化合物(2a～2c和3a～3c).手性CoⅡ(salen)化合物2a～2c在硫醚的不对称氧化反应中显示了中等的反应活性,但只获得了较低对映选择性(8%～21%ee),而手性CoⅢ(salen)化合物3a～3c在该反应中没有反应活性.通过研究整个配体的构象影响对化合物的低对映选择性进行了讨论.