丹参水提液热物性参数测定及模型建立

摘要

Objective To determine the thermal conductivity under different temperatures and concentrations, and specific heat capacity under different concentrations of water extracts of Salvia Miltiorrhiza Radix et Rhizoma; To establish the mathematical model of thermal conductivity-temperature, thermal conductivity-concentration, thermal conductivity-temperature-concentration and specific heat capacity-concentration of water extracts of Salvia Miltiorrhiza Radix et Rhizoma. Methods Thermal conductivity and specific heat capacity were measured by the instantaneous double hot wire thermal conductivity meter and the electrothermal specific heat capacity meter. Excel, 1stOpt and MATLAB were used to analyze the experimental data. Results The method of using brix to facilitate and accurately characterize the concentration was established. The relationship between the thermal conductivity and the temperature and the concentration of water extracts of Salvia Miltiorrhiza Radix et Rhizoma were all linearly negative (λ=a-bT, λ=a-bC), and the influence of temperature and concentration on the thermal conductivity had a certain interaction. λ=a-bC-cT-dCT could be used as the temperature and the concentration on the thermal conductivity of the integrated role model. And the specific heat capacity of the extract was negatively correlated with the concentration (cp=a-bC). Conclusion The thermal conductivity and the specific heat capacity of the extract of water extracts of Salvia Miltiorrhiza Radix et Rhizoma are different at different temperatures and concentrations, and the model can be used to characterize the changing law of thermodynamics of the extracts. It can provide guidance significance for the thermal characteristics analysis in TCM pharmaceutical process and TCM production equipment selection and design, and production process control.%目的 测定丹参水提液在不同温度、不同浓度下的导热系数以及不同浓度下的比热容,建立提取液的导热系数-温度、导热系数-浓度、导热系数-温度-浓度及比热容-浓度的数学模型.方法 采用瞬时双热线法导热系数仪、电热法比热容测定仪测定导热系数和比热容.运用Excel、1stOpt、MATLAB等数据处理软件对实验数据进行分析.结果 建立用白利度来方便、准确表征浓度的方法.初步确定丹参水提液的导热系数与温度、浓度的关系均呈线性负相关(λ=a-bT,λ=a-bC),且温度、浓度对导热系数的影响存在一定相互作用,λ=a-bC-cT-dCT可以作为温度、浓度对导热系数的综合作用模型.初步确定丹参水提液的比热容与浓度呈线性负相关(cp=a-bC).结论 丹参水提液在不同温度、浓度条件下的导热系数和比热容差异较大,建立相关模型能够很好地表征其热物性的变化规律,对中药制药过程的热特性分析和中成药生产设备的选型和设计、生产过程控制等具有指导意义.