mPCNL 术后尿源性脓毒血症危险因素研究

摘要

Objective To explore the risk factors for urosepsis after minimally invasive percutaneous nephrolithot-omy(mPCNL).Methods Clinical data of 1 022 patients undergoing mPCNL were collected,risk factors for urosep-sis after mPCNL were analyzed.Results Of 1 022 patients,62 (6.07%)developed urosepsis.All patients recov-ered and discharged after early diagnosis and active treatment.Logistic regression analysis showed that age(OR95%CI :1 .25-3.92),blood routine examination (OR95%CI :1 .25-14.00),urine routine examination(OR95%CI :2.67-10.02)and volume of intraoperative fluid perfusion(OR95%CI :1 .37-4.18)were closely related to urosepsis fol-lowing mPCNL.Conclusion Age(≥60 years)and intraoperative perfusion fluid volume (≥30L)during operation are the risk factors for urosepsis following mPCNL,The recognition of the related risk factors is helpful for the pre-vention and timely treatment of urosepsis following mPCNL.%目的：了解患者微创经皮肾镜取石术（mPCNL）术后发生尿源性脓毒血症的相关危险因素。方法收集某院1022例患者 mPCNL 围手术期的临床资料，对患者 mPCNL 术后发生尿源性脓毒血症的危险因素进行分析。结果1022例患者，发生尿源性脓毒血症62例，发生率为6．07％。患者经早期发现、积极治疗后均痊愈出院。logistic 逐步回归分析，结果显示，年龄（OR95％CI ：1．25～3．92）、血常规（OR95％CI ：1．25～14．00）、尿常规（OR95％CI ：2．67～10．02）及术中灌注液体量（OR95％CI ：1．37～4．18）与尿源性脓毒血症的发生密切相关。结论年龄（≥60岁）和术中灌注液体量（≥30 L）是患者 mPCNL 术后发生尿源性脓毒血症的危险因素；了解相关危险因素，有助于预防和及时治疗患者 mPCNL 术后尿源性脓毒血症。