苍柏湿毒清对解脲支原体感染小鼠白三烯 C4的影响

摘要

Objectives:To explore the effect of Cangbaishiduqing on the Leukotriene C4 (LTC4)level of Ureaplasma urealyticum(Uu)infected BALB/c mice.Methods:Pretreated by estradiol benzoate under the skin, female BALB/c mice were infected by Uu per vaginam.Mice were treated by different doses of Cangbaishiduqing and its subdivisions.ELISA method was used to test the level of vagina mucosa LTC4.Results:After infection of Uu,the LTC4 level of mice was higher than mice in the blank group (P >0.05).Conclusions:Cangbaishiduqing may not change the level of LTC4 while treating the vaginal infection caused by Uu.%目的：旨在观察苍柏湿毒清对解脲支原体感染 BALB／c 小鼠白三烯 C4（LTC4）的影响。方法：采用小鼠皮下注射苯甲酸雌二醇预处理法，将解脲支原体接种于小鼠阴道，给予不同剂量苍柏湿毒清、苍柏湿毒清拆方灌胃干预，采用 ELASA 法检测小鼠阴道黏膜 LTC4水平。结果：感染解脲支原体后小鼠LTC4水平升高，但与空白组小鼠差异不大（P ＞0.05）。结论：苍柏湿毒清可能不是通过调节 LTC4水平而治疗阴道感染解脲支原体引起的疾病。