帕金森病患者的心理理论障碍

摘要

Objective To characterize social-perceptual component and social-cognitive component of theory of mind(TOM) in patients with Parkinson's disease.Methods A total of 19 patients with idiopathic PD and 20 demographic-matched health subjects were included in this study.They were assessed by using "Reading the Mind in the Eyes" and Faux Pas task involving ToM socialperceptual component and social-cognitive component.The severity of PD was assessed by the Hoehn and Yahr scale.Results Significant difference was found between PD group and health controls in task involving ToM social-perceptual component (mind Reading:17.1 ± 3.1 vs.30.4 ± 1.7,F =278.756,P＜ 0.001),test involving social-cognitive component (Faux Pas Questions:29.0 ± 4.0 vs.41.2±4.4,F=81.647,P＜0.001).While the ability to identify sex and control questions of the Faux Pas showed no significant difference as compared to health controls group (F=3.508,P=0.069;F=1.063,P =0.309).Conclusions The ToM social-perceptual component and social-cognitive component are both impaired in patients with Parkinson's disease.%目的 探讨帕金森病(PD)患者的心理理论(ToM)及其两亚成分加工特点. 方法 将19例PD患者以及与其人口学资料相匹配的20例健康对照组作为研究对象,采用眼区复杂情绪的识别和失言察觉(Faux Pas)任务测试心理理论社会知觉加工和社会认知加工的能力,采用Hoehn-Yahr分级量表对PD患者的严重程度进行评定. 结果 与对照组相比,帕金森病组眼区复杂情绪的识别成绩(17.1±3.1比30.4±1.7,F=278.756,P＜0.001)和失言察觉任务成绩(29.0±4.0比41.2±4.4,F=81.647,P＜0.001)均显著低于对照组,而其性别判断和失言察觉的控制任务与对照组无差异(F=3.508,P=0.069;F=1.063,P=0.309). 结论 PD患者在心理理论加工的两个亚成分上均存在损害.