Objective To observe normal range based on normal adult echocardiography with data mining retrospectively.Methods Analyzed the echocardiography data of 15 553 patients who came to Peking university People's Hospital from Nov 2012 to Nov 2014 without obvious abnormalities of cardiac structure and function.The reference range of 15 parameters were calculated and analyzed in correlation with gender,age and other factors for each group.Results The reference ranges of basic measurement parameters in two-dimensional echocardiography:main pulmonary artery diameter(MPA) (2.14 ± 0.22)cm,diameter of ascending aorta (asc Aorta) (2.87 ± 0.35) cm;The reference ranges of basic measurement parameters in M-mode echocardiography:aortic root diameter (Ao root diam) (2.82 ± 0.35) cm,left atrial dimension (LA dimension) (3.14 ± 0.37) cm,interventricular septal end-diastole thickness (Ⅳsd) (0.86 ±0.12)cm,left ventricular internal diameter at end-diastole (LVIDd)(4.67 ± 0.41)cm,left ventricular internal diameter at end-systole (LVIDs) (2.83 ± 0.34) cm,left ventricular posterior wall end-diastolic thickness(LVPWd) (0.85 ± 0.12) cm,end diastolic volume (EDV) (101.21 ± 19.83) ml,end-systole volume (ESV) (31.09 ± 9.07) ml,ejection fraction (EF) (69.55 ± 5.70) ％;The reference ranges of basic measurement parameters in pulsed doppler echocardiography:mitral A wave velocity (MVA) (73.14 ±16.42) cm/s,mitral E wave velocity(MVE) (84.18 ± 16.17) cm/s,E/A (1.21 ± 0.35),aortic peak velocity (Ao V2 max) (124.95 ± 19.87) cm/s.The measured parameters of males were higher than those of females and value of measured was increased with age for example measured parameters in LVIDd (r =0.225,P =0.00),IVSd(r =0.216,P =0.00),LA dimension (r =0.231,P =0.00) and E/A(r =0.212,P =0.00),with age were positive correlated.The range of 15 parameters in this study and the ASE 2015 guide are similar but have slightly different,such as this research shows that men's left ventricular end-diastolic diameter (4.77 ±0.41) cm,the ASE recommend (5.02 ±0.41) cm which is smaller than the result of this study.And this study for women (4.60 ± 0.40) cm is higher than the ASE recommended (4.50 + 0.36)cm.Conclusions Based on preliminary analysis of large data from normal adult echocardiography,the rang of measured values could be used as a normal reference value of echocardiographyfor routine practice in China.%目的 探讨正常成人超声心动图各基本测量参数的正常参考值.方法 选取2012年11月27日至2014年11月20日在北京大学人民医院门诊就诊及住院的行超声心动图检查结果正常的15553例受检者(男6098例,女9455例),对其超声心动图资料进行回顾性分析,计算不同性别、不同年龄受检者的15个基本测量参数的正常参考值范围,并与性别及年龄等因素进行相关性分析.结果 正常成人二维超声心动图基本测量参数正常参考值范围为:主肺动脉内径(2.14±0.22) cm,升主动脉内径(2.87±0.35) cm;M型超声心动图测量参数正常参考值范围为:主动脉根部内径(2.82 ±0.35) cm,左心房前后径(3.14±0.37) cm,舒张末期室间隔厚度(0.86 ±0.12) cm,左心室舒张末期内径(4.67 ±0.41)cm,左心室收缩末期内径(2.83±0.34)cm,舒张末期左心室后壁厚度(0.85±0.12) cm,舒张末期容积(101.21±19.83) ml,收缩末期容积(31.09±9.07) ml,左心室射血分数(69.55±5.70)％;脉冲多普勒测量参数正常参考值范围为:二尖瓣A峰速度(73.14±16.42) cm/s;二尖瓣E峰速度(84.18±16.17) cm/s,E/A比值(1.21±0.35),主动脉瓣上流速(124.95±19.87)cm/s;男性15个参数测量值均大于女性,均值随年龄增大而增大,其中,左心室舒张末期内径(r=0.225,P=0.00)、舒张末期室间隔厚度(r=0.216,P=0.00)、左心房前后径(r=0.231,P=0.00)和E/A比值(r=0.212,P=0.00)与年龄均呈弱正相关.本研究所得参数与2015年美国超声心动图协会(ASE)指南比较略有差异,本研究显示男性左心室舒张末期内径为(4.77 ±0.41)cm,较ASE推荐值(5.02 ±0.41)cm偏小;女性为(4.60 ±0.40) cm,较ASE推荐值(4.50 ±0.36)cm偏大.结论 通过大数据初步分析正常人群超声心动图结果测量值的正常参考值,可作为临床实际工作的参考.
展开▼
