Ever increasing research find many autoimmune diseases have close relation to intestinal epithelium barrier. This review will provide a progress on the barrier structure, regulation and relation to autoimmune disease.%近年来研究发现很多自身免疫性疾病与肠上皮屏障的功能密切相关,本文着重对肠上皮屏障的基本结构、调控及与自身免疫性疾病的关系作一综述.
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