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USE OF A POLYPEPTIDE FOR EFFECTING IMMUNE SIGNALLING AND/OR AFFECTING INTESTINAL BARRIER FUNCTION AND/OR MODULATING METABOLIC STATUS
USE OF A POLYPEPTIDE FOR EFFECTING IMMUNE SIGNALLING AND/OR AFFECTING INTESTINAL BARRIER FUNCTION AND/OR MODULATING METABOLIC STATUS
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机译:多肽用于影响免疫信号和/或影响肠内屏障功能和/或调节代谢状态的用途
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摘要
It has been found that an extracellular polypeptide derived from Akkermansia municiphila is capable of modulating and/or promoting gut mucosal immune system function and/or maintaining and/or restoring metabolic status and/or increasing the physical integrity of the gut mucosal barrier in a mammal. The polypeptide or host cells including such polypeptide may be employed to prevent and/or treat a variety of conditions that benefit from an increased physical integrity of the gut mucosal barrier and/or an improved gut mucosal immune system function and metabolic status.
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