Objective To observe the relationship between Helicobacter pylori related peptic ulcer and bacterial o-vergrowth in small intestine, and to guide the clinical practice. Methods 78 cases of H. Pylori related peptic ulcer patients and 40 cases of healthy controls were performed glucose breath test. Results The positive rates of SIBO were 4. 3% (2/46) and 6. 3% (2/32) in gastric ulcer and duodenal ulcer group' s. Healthy controls in the basic values and after the test meal in breath hydrogen concentration differences were not statistically significant ( P >0. 05) . Conclusion The patients who had H. Pylori related peptic ulcer do not have bacterial overgrowth in small intestine, so they just accepted therapy for eradication of Helicobacter pylori.%目的 观察幽门螺杆菌(Helicobacter pylori,H.pylori)相关性消化性溃疡有无小肠细菌过度生长,以指导临床实践.方法对78例幽门螺杆菌相关性消化性溃疡组患者和健康对照组患者进行葡萄糖呼气试验.结果 胃溃疡、十二指肠溃疡组小肠细菌过度生长(SIBO)阳性率分别为4.3%(2/46)、6.3%(2/32),胃溃疡组、十二指肠溃疡组、健康对照组在基础值及试餐后氢呼气浓度差异均无统计学意义(P＞0.05).结论 幽门螺杆菌相关性消化性溃疡患者并未出现小肠细菌过度生长,只需进行根除H.pylori治疗.
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