纳米粒子靶向治疗胰腺癌的研究进展

摘要

Pancreatic cancer is a serious malignant tumor with poor prognosis .Although enormous efforts have been made in early detection and comprehensive treatment for this disease , little or no survival improvement was obtained . The progress of nanotechnology based detection and targeted therapy for cancers is rapid with multifunctional nanoparti -cles emerging as one of the most promising approaches .In this paper , the main progress of commonly used nanoparticles and pancreatic cancer nanoparticle therapy was reviewed .%胰腺癌是一种预后极差的恶性肿瘤。虽然目前就胰腺癌的早期诊断和综合治疗投入巨大，但肿瘤患者生存率未见明显改善。随着多功能纳米粒子的合成和应用，纳米技术将快速成为胰腺癌诊断和治疗最有前途的方法之一。本文我们将对常用纳米粒子及胰腺肿瘤纳米治疗的主要进展作一概述。