重症急性胰腺炎临床治疗的研究进展

摘要

Acute pancreatitis (AP) is an acute inflammation of the pancreas, may be involved in pancreatic tissue around or distant organ system.Among them, severe acute pancreatitis (SAP) is a serious disease, more complications, poor prognosis and high mortality rate of acute abdomen, the overall mortality rate of patients is 20%.When organ failure and septic necrosis occur, the mortality rates are increased to 30% and 32%, respectively, and the SAP patients usually die within a week.At present, SAP treatment emphasizes the individualized and comprehensive treatment, medicine conservative treatment should be used firstly, according to different situations, minimally invasive or surgical treatment should be chosen reasonably.This paper introduced a brief comprehensive clinical treatment on SAP in recent years.%急性胰腺炎(acute pancreatitis,AP)是胰腺的急性炎症状态,可能涉及胰腺周围组织或远隔器官系统.其中,重症急性胰腺炎(severe acute pancreatitis,SAP)是一种病情凶险、并发症多、预后差、病死率较高的急腹症,其总体病死率为20%.SAP患者一旦发生器官衰竭及感染性坏死,病死率则分别提高到30%和32%,且通常在1周内死亡.目前对SAP的治疗临床上强调个性化综合治疗,应首先采用内科保守治疗,并针对不同情况合理选择微创或手术治疗.本文就近年来SAP的临床治疗进展作一概述.