目的：本研究旨在探讨采用胆道修复术对胆管大范围缺损Mirizzi综合征患者进行治疗的临床疗效及安全性，为临床治疗提供参考意见。方法回顾性分析在本院行胆道修复术的22例胆管大范围缺损Mirizzi综合征患者的治疗手段和临床疗效，其中有12例采用带血管蒂胃瓣修补治疗，10例行带脐静脉瓣胆道修复术，对两组患者的一般资料、临床资料及治疗结果进行对比分析。结果两组患者的临床资料比较差异无显著性（P＞0.05）；胃瓣修补组和脐静脉瓣修复组发生的术后并发症主要为胆管炎症，分别为4例（33.33%）和3例（30%），各组不良反应分别相加得出胃瓣修补组8例，脐静脉瓣修复组5例，两组采用Fisher精确检验得出P＞0.05，两组术后不良反应差异无显著性。结论对胆管大范围缺损Mirizzi综合征患者采取胆道修复术（脐静脉瓣胆道修复术、带血管蒂胃瓣修补术）均是行之有效的治疗措施，术后并发症状轻微，无死亡病例发生，可以作为Mirizzi综合征患者的首选治疗措施。%ObjectiveTo investigate the prosthesis operation of bile duct for clinical efifcacy and safety of treatment for bile duct defects in patients with Mirizzi syndrome, and provide a reference for the clinical treatment of bile duct defects in Mirizzi syndrome.MethodsA retrospective analysis of 22 cases of bile duct defects in Mirizzi under went biliary tract prosthesis syndrome treatment and clinical curative effect of the patients, including 12 cases with vascular pedicled gastriclfap for repair of treatment, 10 cases with umbilical vein graft repair of biliary tract, carries on the contrast analysis to the general data, clinical data of two groups of patients and treatment results.ResultsThe clinical data of two patients were not statistically signiifcant (P>0.05); gastric lfap in the repair group and umbilical venous lfap group,postoperative complications occurring mainly for bileduct inlfammation, were 4 (33.33%) and 3 (30%), each dystrophy respectively sum gastriclfap in the repair group 8 cases, umbilical vein lfap in 5 cases repair group, the two groups using Fisher's exact test shows thatP>0.05, two groups of symptoms after surgery no signiifcant difference.ConclusionTake the prosthesis operation of bile duct to duct defects in patients with Mirizzi syndrome (repair, umbilical vein graft with vascular pedicle lfap of stomach bile duct repair) are effective treatment, postoperative symptoms are mild, no deaths occurred, can be the preferred treatment for patients with Mirizzi syndrome.
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