疏血通注射液联合盐酸氟桂利嗪胶囊治疗椎-基底动脉供血不足性眩晕55例疗效观察

摘要

ObjectiveTo evaluate the combination of injections and Shuxuetong flunarizineHcl treatment of vertebral-basilar artery insufifciency vertigo effect, in order to improve the clinical application.Methods March 2009 to March 2012 in our hospital 110 cases of vertebral - basilar artery insufficiency vertigo patients were randomly divided into treatment and the principle of the control group, 55 cases. Treatment group to 6 ml injection Shuxuetong plus 250 ml 0.9% NaCl intravenous injection, 1 time/day, 5 mg flunarizineHcl nightly bedtime. In the control group to 20 ml Salvia injection plus 250 ml 0.9% NaCl intravenous injection, 1 times/day. 2 weeks after treatment were observed. Results The treatment group was 94.55%, the control group was 72.73%, comparing the two groups there was a significant difference (P < 0.05). The onset time required for drug treatment group compared with the control group earlier, there was a significant difference (P < 0.05) between the two groups compared. Before and after treatment, the treatment group bilateral vertebral artery and basilar artery mean blood velocity contrast there was a significant difference (P < 0.01), before and after treatment compared to the control group and the treatment group showed significant differences (P < 0.05), described the treatment group than the control group. Conclusion Shuxuetong injection flunarizineHcl combined treatment vertebral-basilar artery insufficiency vertigo treatment exactly worthy to be popularized in clinical practice.%目的：探讨联合应用疏血通注射液和盐酸氟桂利嗪胶囊治疗椎-基底动脉供血不足性眩晕的疗效，以完善临床应用。方法选取2009年3月至2012年3月于本院就诊的110例椎-基底动脉供血不足性眩晕患者，采用随机化原则分为治疗组和对照组，各55例。治疗组予6 ml注射用疏血通加250 ml 0.9% NaCl注射液静脉滴注，1次/日，5 mg盐酸氟桂利嗪胶囊于每晚睡前服用。对照组予20 ml丹参注射液加250 ml 0.9% NaCl注射液静滴，1次/日。2周后观察两组治疗效果。结果治疗组有效率为94.55%，对照组有效率为72.73%，两组对比有显著性差异（P＜0.05）。治疗组用药起效所需时间较对照组早，两组之间对比有显著性差异（P＜0.05）。用药前后，治疗组双侧椎动脉和基底动脉平均血液流速对比有显著性差异（P＜0.01），治疗前后对照组与治疗组相比均有显著性差异（P＜0.05），说明治疗组疗效优于对照组。结论疏血通注射液联合盐酸氟桂利嗪胶囊治疗椎-基底动脉供血不足性眩晕治疗效果确切，值得在临床加以推广应用。