Objective To compare the anesthetic effect and postoperative pain in patients undergoing laparoscopic cholecystectomy with Sevoflurane inhalation anesthesia and Propofol intravenous anesthesia. Method 80 patients underwent laparoscopic cholecystectomy from March 2015 to October 2016 in our hospital were randomly divided into study group and control group, 40 cases in each group. Patients in control group were treated with Propofol intravenous anesthesia, patients in study group were treated with Sevoflurane inhalation anesthesia. The time of extubation, awakening time after anesthesia, observer's assessment of alertness/sedation scale (OSS/A) scores of 5 minutes after extubation, the rate of agitation and pain after palinesthesia, the awareness rate in the operation, anesthetic effect, incidence rate of adverse reactions were compared between the two groups. Result The time of extubation and awakening of study group were significantly shorter than those of control group (P < 0.05), the OAA/S score and total excellent rate of study group was higher than that of control group (P < 0.05), the incidence rates of agitation and pain after palinesthesia, intraoperative awareness and adverse reactions of study group were lower than those of control group (P < 0.05). Conclusion Sevoflurane anesthesia can shorten extubation time and awakening time after anesthesia, reduce the rate of agitation and pain after palinesthesia, reduce adverse reactions, the anesthetic effect is better than Propofol intravenous anesthesia.%目的 比较七氟醚吸入麻醉和丙泊酚静脉麻醉对腹腔镜胆囊切除术患者的麻醉效果及其术后疼痛发生情况.方法 选取2015年3月至2016年10月本院收治的腹腔镜胆囊切除术患者80例为研究对象,采取盲选法将其分为研究组和对照组,每组各40例.对照组患者采用丙泊酚单纯静脉麻醉,研究组患者采用七氟醚吸入麻醉.比较两组患者的拔管时间、麻醉后苏醒时间、拔管后5分钟警觉-镇静(observer's assessment of alertness/sedation scale,OAA/S)评分、苏醒后躁动和疼痛的发生率、术中知晓率、麻醉效果及不良反应发生率.结果 研究组患者的拔管时间、苏醒时间均明显短于对照组(P<0.05),OAA/S评分和总优良率均明显高于对照组(P<0.05),苏醒后躁动和疼痛的发生率、术中知晓率及不良反应总发生率均低于对照组(P<0.05).结论 采用七氟醚吸入麻醉可缩短拔管时间和苏醒时间,降低苏醒后躁动和疼痛的发生率,减少不良反应,麻醉效果优于丙泊酚静脉麻醉.
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