糖化血红蛋白水平在预测妊娠期糖尿病孕妇生产结局中的价值分析

摘要

目的 探讨糖化血红蛋白(glucosylated hemoglobin,HbAlc)水平在预测妊娠期糖尿病(gestational diabetes mellitus,GDM)孕妇生产结局中的价值.方法 将2014年6月至2015年12月在四川省眉山市妇幼保健院进行产前检查并在该院分娩的146例GDM孕妇,按照分娩前HbAlc水平控制情况将其分为控制组86例、未控制组60例,另外选取同期HbAlc水平正常的产妇60例作为对照组,对比分析3组产妇妊娠结局.结果 未控制组妊娠期高血压疾病、胎膜早破、羊水过多、剖宫产率、羊水粪染、早产、胎儿宫内窘迫、新生儿窒息和巨大儿发生率明显高于控制组和对照组(P<0.05),控制组和对照组比较差异无统计学意义(P>0.05).结论 HbAlc水平对GDM孕妇的妊娠结局有较好的预测作用,可将HbAlc水平作为孕妇血糖控制情况的重要监测指标.%Objective To investigate the value of glycosylated hemoglobin(HbAlc) level in predicting the outcomes of pregnant women with gestational diabetes mellitus(GDM). Methods 146 pregnant women diagnosed with GDM in Meishan Women and Children's Hospital from June 2014 to December 2015 were divided into control group(86 cases) and non-control group(60 cases). 60 women with normal HbAlc levels were selected as the matched group. The pregnancy outcomes of the three groups were analyzed. Results The proportion of pregnancy induced hypertension, premature rupture of membranes, polyhydramnios, cesarean section, meconium stained amniotic fluid, premature delivery, fetal distress, neonatal asphyxia and giant baby in non -control group were significantly higher than that of the control group and the matched group, the differences were statistically significant(P < 0.05). While the differences between the control group and the matched group had no statistical significance(P>0.05).Conclusion The level of HbAlc has a good predictive effect on the production of GDM pregnant women.It can be used as an important monitoring index of blood glucose control in pregnant women with GDM.