目的 了解我国不同民族的健康人群戊型肝炎病毒感染情况.方法 采用ELISA方法检测人群血清中戊型肝炎病毒(戊肝,HEV)IgG抗体.汉族人群血清分别来自于四川、北京、黑龙江和山东,回族和藏族人群血清来自于甘肃、宁夏和青海,总共10 448份血清采集于2006 -2008年.结果 七省市人群HEV抗体总阳性率为17.97％(1878/10 448).汉、回和藏不同民族人群HEV抗体阳性率分别为24.32％ (1794/7376)、3.59％(81/2258)和0.37％(3/814).不同地区人群HEV抗体阳性率分布,四川、北京、黑龙江和山东汉族人群阳性率分别为27.45％、20.30％、22.89％和22.68％,甘肃汉和回族分别为24.63％( 184/747)和6.12％( 77/1258),宁夏回族和青海藏族分别0.40％和0.37％.汉回藏不同民族各年龄组人群HEV感染分布,汉族各年龄组人群HEV抗体阳性率,在≤10岁年龄组为5.19％,11～20岁组为11.64％,21 ～ 30岁组为20.08％,31 ～ 40岁组为34.17％,41 ～50岁为41.75％,51 ～60岁组为48.58％,≥61岁组为57.43％.回族人群各年龄组人群HEV抗体阳性率依次为3.11％,3.96％,2.11％,3.98％,2.52％,4.57％和6.67％.藏族人群3份阳性者分布在21～30岁组、31 ～40岁组和51 ～60岁组各1份,阳性率为0.63％、0.58％和1.01％.结论 汉族人群戊肝病毒感染明显高于回族和藏族,感染率随年龄增长而升高.回藏族人群HEV抗体阳性率低下,应加强对HEV感染的监测.%Objective To investigate the seroprevalence of HEV infection in different national human population in Han,Hui and Zang in China.Methods EIA was used for detecting anti-HEV IgC of the serum samples.All samples were collected in 2006-2008 in Sichuan,Beijing,Heilongjianin,Sandong,Gansuo,Ningxia and Qinghai areas.Results The total positive rate of anti-HEV IgG was 17.97％ (1878/10448),24.32％ ( 1794/7376)in Han national,3.590％ ( 81/2258) of Hui national and 0.37％ ( 3/814) of Zang national,respectively.The positive rate of Han human at different age group, was 5.1g％ of≤ 10year,11.64％ of 11 - 20 year,20.08％ of 21 - 30 year,34.17％ of 31 - 40 year,41.75％ of 41 - 50 year,48.58％ of 51 - 60 year,57.43％ of≥ 61 year. The positive rate of Hui human at different age group, was 3.11％, 3.96％,2.11％, 3.98, 2.52％,4.57％ and 6.670％, respectively. Three positive of Zang human was between 21 - 60 year. Conclusions The HEV infection in Han national population was higher than the Hui and Zang national,significantly.The HEV infection was correlation with age significantly, the infection rate was increased with age.
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