偏倚风险评估系列:(九)如何应用偏倚风险评估的结果

摘要

本文为偏倚风险评估系列讲座的最后一节,主要讨论偏倚风险评估结果的应用.偏倚风险评估是证据质量评估中关键的一环,能为循证决策提供重要的参考依据.偏倚风险评估结果可以用于单个研究的偏倚风险诊断,其结果可影响系统综述中对于原始研究的纳入排除和数据的分析.此外,本文重点讨论偏倚风险评估的结果如何应用到推荐分级的评价、制订与评估(GRADE)的整体证据质量评价,包括证据质量评价中的原则以及注意事项.%In this last paper of the series about risk of bias assessment,we introduce the application of risk of bias assessment results.Risk of bias assessment is one of the key steps in the assessment of quality of evidence.The risk of bias assessment results could be the “diagnosis” of individual studies,which helps decision making related to the inclusion and exclusion of individual studies,as well as the data analysis in the systematic review process.This paper focuses on how to incorporate risk of bias assessment results in the GRADE assessment for quality of evidence,including the principles and the tips for the application.