男男性行为人群利用艾滋病病毒抗体唾液快速检测试剂自检的可接受性调查

摘要

目的 评估MSM对HIV抗体口腔黏膜渗出液检测试剂自检(口腔自检)方式检测HIV的可接受度.方法 2013年4月至2014年4月在北京市和南宁市招募MSM进行基线和随访调查,包括问卷调查、HIV血清学检测(HIV血检)和口腔快检自检.通过平行对比血检和口腔自检得到口腔自检的灵敏度和特异度,通过logistic回归模型评估MSM对口腔快检的可接受度和相关影响因素.结果 510名MSM参加基线调查,其中279名接受门诊随访调查.基线MSM口腔自检的灵敏度86.00％(43/50),特异度98.23％(445/453).基线MSM中有78.63％(401/510)报告在本次研究后有口腔自检HIV的意愿,相关因素包括最近6个月与固定性伴不使用安全套肛交(aOR=0.30,95％CI:0.10～ 1.00)和首选检测方式为口腔快检(aOR=7.32,95％CI:1.61 ～ 33.31).相较血检,基线MSM中34.51％ (176/510)报告更倾向于进行口腔快检,相关因素为出生地在城市.结论 中国两城市MSM对HIV口腔自检方式可接受度高.%Objective To evaluate the acceptability of oral quick HIV self-testing in men who have sex with men (MSM).Methods From April 2013 to April 2014,MSM in Beijing and Nanning of China were recruited for an observational study including baseline survey and follow-up,including questionnaire survey,oral HIV self-testing and clinic-based HIV confirmation testing.The sensitivity and specificity of oral quick self-testing were evaluated through comparing the results of oral quick testing with blood testing.The acceptability and associated factors were evaluated by logistic model.Results A total of 510 MSM were recruited at baseline survey and 279 accepted follow-up.The sensitivity of the oral self-test was 86.00％ (43/50) and specificity was 98.23％ (445/453) at baseline survey.At baseline survey,78.63％ (401/510) of the MSM showed willingness to use oral quick HIV self-testing.The associated factors included unprotected anal intercourse with a regular male partner in the past 6 months (aOR=0.30,95％ CI:0.10-1.00) and preference of oral quick HIV self-testing (aOR=7.32,95％CI:1.61-33.31).At baseline survey,34.51％ (176/510) of the MSM reported that oral quick HIV self-testing was the preferred testing method rather than blood testing,which was associated with their birth places-urban area.Conclusion The acceptability of oral quick HIV self-testing in MSM in the two cities was high.