目的：探讨手术年龄对行关节置换术的老年膝关节退行性骨关节炎疗效的影响。方法选择128例老年膝关节退行性骨关节炎患者，根据年龄将其分为2组，即60～70岁为I组78例，71～80岁为II组50例。观察术后2组患者骨关节炎指数评分（WOMAC）、简易精神状态检查评分（mMMSE）、生存质量信度评分（SF-12）以及日常生活能力评分（ ADL）改善情况，记录2组患者手术时间及术中出血量，以及随访评价疼痛控制情况。结果与II组比较，I组WOMAC、mMMSE评分降低明显，手术时间及术中出血量较少[（72 W．6±10．0）分vs．（78．7±11．3）分、（11．3±2．0）分vs．（12．8±2．1）分、（132±21）min vs．（158±23）min、（268±131）ml vs．（353±145）ml]，差异均有统计学意义（ P ＜0．01），而SF-12、ADL评分差异无统计学意义（ P ＞0．05）；随访中发现，2组手术并发症、疼痛各级评定比较差异无统计学意义（ P ＞0．05）。结论老年膝关节退行性骨关节炎患者行关节置换手术的最佳时机为60～70岁。%Objective To investigate the effect of age on the operation of joint replacement in elderly patients with knee osteoarthritis .Methods Selected 128 cases of senile knee osteoarthritis patients , according to age , they were divided in-to 2 groups, 60-70 years old of 78 cases in group I, 71-80 years old of 50 cases in group II.Observed 2 groups of patients’ bone arthritis index (WOMAC), Mini Mental State Examination (mMMSE) score, quality of life reliability score (SF-12) and activity of daily living score ( ADL) to improve the situation , recorded 2 groups of patients with operation time and blee-ding amount and intraoperative , follow-up evaluation of pain control .Results Compared with group II , WOMAC, mMMSE score decreased significantly in group I, operation time and bleeding volume were less [(72.6 ±10.1) vs.(78.7 ±11.3), (11.3 ±2.0) vs.(12.8 ±2.1), (132 ±21) min vs.(158 ±23) min, (268 ±131) ml vs.(353 ±145) ml], the diffe-rence was statistically significant ( P <0.01), but no statistical significance of SF-12 and ADL score ( P >0.05); during follow-up, operation complications and pain levels assessment revealed no statistical significance differences between the 2 groups ( P >0.05).Conclusion The best time of elderly knee osteoarthritis arthroplasty operation is 60-70 years old.
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