2型糖尿病中免疫异常的研究进展

摘要

[Summary] The incidence of diabetes mellitus is increasing year by year ,which attracts more and more attention. Scientific researches have demonstrated the role of chronic systemic inflammation and immune dysregulation in the development of type 2 diabetes mellitus (T2DM ). Moreover ,the evidence of islet autoimmunity has also been identified in some patients with T 2DM. These discoveries highlight the potential of immune‐modulatory therapies for T 2DM.%糖尿病的发病率逐年上升，引起人们越来越多的关注。研究表明，T2DM 发病机制中存在慢性炎症和免疫调节异常，在一些患者中还发现了胰岛自身免疫的证据。因此，免疫调节治疗成为治疗T2DM 的新思路。