高能紫外光联合点阵铒激光治疗白癜风的疗效观察

摘要

目的 评价304 nm高能紫外光联合2 940 nm点阵铒激光治疗白癜风的疗效及安全性.方法 将64例局限型白癜风患者随机分成2组,治疗组32例采用高能紫外光联合点阵铒激光治疗,对照组32例仅予高能紫外光照射.2组均每周治疗2次,3个月为1个疗程,共2个疗程.结果 治疗1个疗程后观察看到,治疗组有效率68.75％,对照组有效率56.25％,2组治疗白癜风的有效率差异无统计学意义(P＞0.05).治疗2个疗程后观察看到,治疗组有效率93.75％,对照组有效率75％,2组治疗白癜风的有效率差异有统计学意义(P＜0.05).结论 304 nm高能紫外光联合2 940 nm点阵铒激光治疗局限型白癜风起效更快,疗效肯定,是一种简单、安全的治疗方法.%Objective In order to evaluate the efficacy and safety of application of high-energy ultraviolet (UV) combined with erbium fractional laser in treating vitiligo.Methods A randomized experimental controlled study was performed in 64 patients,and they were randomly divided into two groups:group A receiving erbium fractional laser and Dualight UVB therapy;group B singly receiving Dualight UVB therapy.All patients were treated twice a week.Results After therapy for six months,the response rates were 93.75％ and 75％ respectively in group A and group B.The response rate was higher in group A than group B(P＜0.05).Conclusion High-energy UV combined with erbium fractional laser therapy has better efficacy for stable vitiligo than single treatment.Combination therapy of high-energy UV and erbium fractional laser is safe,effective and well-tolerated for vitiligo.