肠系膜下动脉结扎方式对乙状结肠癌及直肠癌生存预后的Meta分析

摘要

目的:采用Meta分析方法探讨肠系膜下动脉结扎方式对乙状结肠癌及直肠癌患者生存预后及复发率的影晌.方法:应用知网、万方、Cochrane图书馆、CBM等搜索引擎,结合手工检索方式,检索收集201 0年1月-2016年1月国内外有关肠系膜下动脉结扎方式对乙状结肠癌及直肠癌患者术后生存预后以及肿瘤复发率影响的相关文献,进行Meta分析.结果:本次共筛选出符合标准的参考文献1 1篇,肠系膜下动脉结扎方式有低位结扎与高位结扎两种,不同结扎方式的生存预后与术后复发率比较差异无统计学意义(P＞0.05).结论:肠系膜下动脉高位结扎与低位结扎对乙状结肠癌及直肠癌患者的生存预后并无明显差异,且两种结扎方式的术后复发率也比较接近,目前并没有太多证据能证明高位结扎更具优势.%Objective:To investigate the effect of ligation of inferior mesenteric artery on the survival outcome and recurrence rate of patients with sigmoid colon cancer and rectal cancer by Meta analysis.Methods:CNKI,Wan Fang,Cochrane library,CBM and other search engines,combined with manual retrieval method,retrieval from January 2010 to January 2016,domestic and foreign literature about the inferior mesenteric artery ligation in sigmoid colon and rectal cancer patients with postoperative survival and tumor recurrence rate,using the Meta analysis method to summarizeand analyze the.Results:the total screened met the inclusion criteria and exclusion criteria of the 11 references,there are two kinds of low ligation and high ligation of inferior mesenteric artery ligation,recurrence and prognosis of different ligation mode,no statistical significance (P＞0.05).Conclusion:the inferior mesenteric artery ligation and high ligation of the sigmoid colon and rectal cancer patients survival did not differ significantly,and the two kinds of ligation of the postoperative recurrence rate is relatively close,there is not much evidence that high ligation has more advantages.