Objective To analyze ihe clinical characlerislics of acule myocardial infarclion due Lo occlusion of circumflex artery. Methods We relrospeclively analyzed ihe clinical characlerislics, ECG alleralion, coronary angiographic features and ihe mortality of 242 palienls wilh acule myocardial infarclion (190 males and 52 females respectively) , who underwent elective or urgent PCI wilhin 7 days after infarclion. Results All patienls were divided into ihree groups according to infarcl - related artery. The infarcl - relaled vessel was the lefl anterior descending artery in 117 patienls (48. 3% ) , the lefl circumflex in 31 cases( 12. 8% ) and the righl coronary artery in 94(38. 3% ) . The mortality during hospilalization of ihree groups was 6. 0% , 3. 2% and 3. 2% , respectively. The difference was nol significant(P = 0. 591). Ill cases of anterior descending artery group and 10 patienls in circumflex artery group had significant ECG alleralion (94. 87% and 32. 26% , P < 0. 01 ). The peak value of creatine kinase and creatine kinase isoenzyme of anterior descending artery group increased significantly (P<0. 05) , accompanied wilh significantly reduced lefl ventricular ejection frac lions (P <0. 05) . The proportion of non ST - segment elevalion myocardial infarction was more lhan thai of ST - segment elevalion myocardial infarction in circumflex artery group. The proportion of non ST - segmenl elevation myocardial infarclion is 51. 61% in circumflex artery group, 19. 66% in anlerior descending artery group and 18.95% in righl coronary artery group, respectively(P <0. 01) . Conclusion Acule ST - segment elevalion myocardial infarction (STEMI) due lo occlusion of circumflex artery is supposed lo have a low morbidity, and high false negalive ECG diagnosis. So the early definile diagnosis is not easy. Nevertheless, we should pay more atlention lo circumflex artery relaled infarction in regard lo its high mortality during hospilalization.%目的 分析由回旋支(LCX)闭塞引起的急性心肌梗死(AMI)患者的临床特征.方法 回顾性分析我院因AMI收住院并在发病7 d内行经皮冠状动脉介入(PCI)治疗的患者242例(男190例,女52例)的临床资料,对其临床特征、心电图表现、冠状动脉病变特点及住院期间死亡率进行分析比较.结果.前降支为梗死相关动脉的为117例(占48.3%),回旋支为梗死相关动脉的为31例(占12.8%),右冠状动脉为梗死相关动脉有94例(占38.8%);院内死亡率分别为6.0%、3.2%及2.0%,差异无统计学意义(P=0.591).心电图有明显定位改变的分别为前降支组111例占94.87%,回旋支组10例占32.26%,右冠状动脉组71例占74.74%,差异有统计学意义(P<0.01);前降支组的肌酸激酶和肌酸激酶同工酶峰值较其他两组明显升高(P<0.05),左室射血分数(LVEF)明显降低(P<0.05),但回旋支组中非ST段抬高心肌梗死的比例明显高于ST段抬高心肌梗死,回旋支组中非ST段抬高心肌梗死比例为51.61%,前降支组为19.66%,右冠状动脉组为18.95%,差异有统计学意义(P<0.01).结论.由回旋支闭塞引起的AMI发病率较低,早期不易得到明确诊断,就诊时心电图无明显定位的病例多,但由其引起的院内死亡率并不低,应引起重视.
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