体位性心动过速综合征（ postural tachycardia syndrome ， POTS）是直立不耐受的最常见表现之一，可有直立体位的大脑低灌注和交感神经过度兴奋的临床症状，包括轻度淡漠、视物模糊、认知障碍和虚弱、心悸、胸痛及震颤等，卧位可缓解，部分患者可有直立诱发的血管迷走性晕厥。 POTS表现多样，发病机制较复杂，可能与免疫、基因变异、神经系统传导和调节功能、精神心理因素等相关，治疗上需要根据具体类型和发病机制选择不同的方案。%Postural tachycardia syndrome (POTS) is one of the most common manifestations of orthostatic intolerance , with symptoms of cerebral hypoperfusion and excessive sympathoexcitation , including light -headedness , blurred vision , cognitive difficulties , and generalized weakness , palpitations, chest pain, and tremulousness, which can be relieved by recumbency .Some patients developed vasovagal syncope that is initiated by orthostatic stress . POTS has differential clinical characteristics and multiple interacting pathophysiologic mechanisms .Relationships of POTS and immune disorders, gene variations, neural reflex and modulation disorders , cognitive factors, are well studied. Managements of patients with POTS should be altered according to the subtypes and pathophysiology of POTS.
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